Some people tell me I think too much. That's quite surprising to another set who believe I think very little. But, whatever the truth is, I do tend to ask questions just for understanding. One question that arose was:
"When was the first dementia diagnosis and how did it lead to where Science is today?"
Going through the maze of articles and finding very little, at first, I was discovering that not many of the sites dedicated to the types of dementia had much to tell me as to the actual history of the affliction. This was disheartening, but it made it a challenge. So, despite the clinical findings, I was able to locate some information in some pretty interesting places.
It was in 1906 that Alois Alzheimer began to study a patient who exhibited severe memory loss and profound paranoia about his family. Upon autopsy, he noted severe shrinkage of the brain along with abnormal deposits. This was the first recognition of the condition known now as Alzheimer's Dementia. (http://www.alz.org/research/science/major_milestones_in_alzheimers.asp)
In 1910, the condition was formally named after the doctor who documented it four years earlier.
In 1931, the electron microscope was invented and introduced as a method for scientists to begin studying brain cells in more detail.
In 1968, there were the first validated scales of cognitive measurement introduced to assess the older adults who were deemed impaired due to the lesions or abnormal brain functions due to such deposits.
1974 - Congress establishes the National Institutes on Aging (the NIA).
Thus began the life of the Alzheimer's Association and the research into dementia.
In 1912, Dr, Fritz Heinrich Lewy discovered the neuronal abnormal deposits of protein that would be later named for him. These would not be recognized in the cortical context until the mid 1980's when it was seen as a form of Alzheimer's disease ("Lewy Body variant of Alzheimer's disease"). Finally, in 1999-200it was termed "diffuse Lewy Body Dementia".
In 1995 and 2005, there was a consortium to determine the clinical guidelines for diagnosis. As of this writing, there is discussion of another in order to further develop and guide the neurologists in making the determining diagnosis (MedMerits: Dementia with Lewy Bodies).
MedMerits: Dementia with Lewy Bodies
National Institute on Aging
"When was the first dementia diagnosis and how did it lead to where Science is today?"
Going through the maze of articles and finding very little, at first, I was discovering that not many of the sites dedicated to the types of dementia had much to tell me as to the actual history of the affliction. This was disheartening, but it made it a challenge. So, despite the clinical findings, I was able to locate some information in some pretty interesting places.
It was in 1906 that Alois Alzheimer began to study a patient who exhibited severe memory loss and profound paranoia about his family. Upon autopsy, he noted severe shrinkage of the brain along with abnormal deposits. This was the first recognition of the condition known now as Alzheimer's Dementia. (http://www.alz.org/research/science/major_milestones_in_alzheimers.asp)
In 1910, the condition was formally named after the doctor who documented it four years earlier.
In 1931, the electron microscope was invented and introduced as a method for scientists to begin studying brain cells in more detail.
In 1968, there were the first validated scales of cognitive measurement introduced to assess the older adults who were deemed impaired due to the lesions or abnormal brain functions due to such deposits.
1974 - Congress establishes the National Institutes on Aging (the NIA).
Thus began the life of the Alzheimer's Association and the research into dementia.
In 1912, Dr, Fritz Heinrich Lewy discovered the neuronal abnormal deposits of protein that would be later named for him. These would not be recognized in the cortical context until the mid 1980's when it was seen as a form of Alzheimer's disease ("Lewy Body variant of Alzheimer's disease"). Finally, in 1999-200it was termed "diffuse Lewy Body Dementia".
In 1995 and 2005, there was a consortium to determine the clinical guidelines for diagnosis. As of this writing, there is discussion of another in order to further develop and guide the neurologists in making the determining diagnosis (MedMerits: Dementia with Lewy Bodies).
Resources
Major Milestones in Alzheimer's and Brain ResearchMedMerits: Dementia with Lewy Bodies
National Institute on Aging
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